A new study found that exercise can help reduce pain and inflammation, while increasing the body’s “cannabis-like” substances. This may have a positive impact on various situations.
exercise It is well known that the University of Nottingham can reduce chronic inflammation that can lead to diseases such as arthritis and cancer famous In the press release.
“In particular, animal models and human studies have shown that exercise can increase the relative abundance of butyric acid-producing microorganisms, thereby increasing the production of butyric acid, which is a short-chain fatty acid with systemic anti-inflammatory effects,” a new study Said the researchers. Learn, Publish Said in the Journal of Gut Microbiome.
However, the university pointed out that there is “not much knowledge” about how it reduces inflammation.
The researchers conducted their study with the help of 78 arthritis patients. Among the participants, 38 had 15 minutes of muscle-strengthening exercise intervention every day for six weeks, while the rest did not.
They found that those who performed exercise intervention reduced pain and lowered the level of inflammatory substances (cytokines).They also have more gut microbes that produce anti-inflammatory substances, and higher levels Endocannabinoids, They are molecules similar to the cannabinoids found in marijuana, but produced by the body.
“The increase in endocannabinoids is closely related to the changes in intestinal microbes and anti-inflammatory substances produced by intestinal microbes, called SCFA,” explained the University of Nottingham. “In fact, at least one-third of the anti-inflammatory effects of the gut microbiome are due to the increase in endocannabinoids.”
The researchers pointed out that the results indicate that the anti-inflammatory effects of short-chain fatty acids are “partly mediated by the endocannabinoid system.” The university noted that overall, exercise intervention seems to usher in these changes by affecting the gut microbiota, adding that it may help treat diseases such as arthritis and heart disease.
“Our research clearly shows that exercise increases the body’s own cannabis-like substances. This can have a positive effect on many situations,” Dr. Amrita Vijay, the first author of the study, said in a press release. “As interest in cannabidiol oil and other supplements increases, it is important to know that simple lifestyle interventions such as exercise can modulate endocannabinoids.”
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